MSTN Antikörper (AA 281-375)

Produktnummer ABIN674469

Dieses Anti-MSTN-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MSTN in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human, Maus, Ratte und Schwein. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für MSTN Antikörper (AA 281-375) (ABIN674469)

Target: MSTN (Myostatin (MSTN))

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSTN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MSTN Antikörper

Bindungsspezifität: AA 281-375

Kreuzreaktivität: Human, Maus, Schwein, Ratte

Homologie: Cow,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDF8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-MSTN Antikörper (ABIN674469)

Qian, Tang, Yang, Wang, Cai, Jiang, Li, Jiang, Gao, Ma, Chen, An, Li, Cui: "Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs." in: Scientific reports, Vol. 5, pp. 14435, (2016) (PubMed).

Details zu MSTN

Target: MSTN (Myostatin (MSTN))

Andere Bezeichnung: GDF8/MSTN

Hintergrund:

Synonyms: GDF8, MSLHP, Growth/differentiation factor 8, GDF-8, Myostatin, MSTN

Background: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth. [SUBUNIT] Homodimer, [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. Belongs to the TGF-beta family.

Gen-ID: 2660

UniProt: O14793