HLA-E Antikörper (AA 251-358)
Kurzübersicht für HLA-E Antikörper (AA 251-358) (ABIN674334)
Target
Alle HLA-E Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 251-358
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human HLA E
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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: "High NKG2A expression contributes to NK cell exhaustion and predicts a poor prognosis of patients with liver cancer." in: Oncoimmunology, Vol. 6, Issue 1, pp. e1264562, (2017) (PubMed).
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: "High NKG2A expression contributes to NK cell exhaustion and predicts a poor prognosis of patients with liver cancer." in: Oncoimmunology, Vol. 6, Issue 1, pp. e1264562, (2017) (PubMed).
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- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
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Andere Bezeichnung
- HLA E
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Hintergrund
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Synonyms: MHC, QA1, EA1.2, EA2.1, HLA-6.2, HLA class I histocompatibility antigen, alpha chain E, MHC class I antigen E, HLA-E, HLAE
Background: HLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules.
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Gen-ID
- 3133
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UniProt
- P13747
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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