Claudin 18 Antikörper (C-Term)

Produktnummer ABIN214745

Der Kaninchen Polyklonal Anti-Claudin 18-Antikörper wurde für WB, IHC und IHC (p) validiert. Er ist geeignet, Claudin 18 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd und Affe zu detektieren.

Kurzübersicht für Claudin 18 Antikörper (C-Term) (ABIN214745)

Target: Claudin 18 (CLDN18)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Claudin 18 Antikörper

Bindungsspezifität: C-Term

Marke: IHC-plus™

Spezifität: Human CLDN18 / Claudin 18

Homologie: Percent identity by BLAST analysis: Human, Mouse, Rat (100%) Rabbit (92%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide from C-Terminus of human CLDN18 (P56856, NP_001002026). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Bovine, Horse (100%), Elephant, Rabbit, Guinea pig (92%), Panda (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Details zu Claudin 18

Target: Claudin 18 (CLDN18)

Andere Bezeichnung: CLDN18 / Claudin 18

Hintergrund: Name/Gene ID: CLDN18
Family: Claudin

Synonyms: CLDN18, Claudin 18, Claudin-18, SFTPJ, SFTA5, Surfactant associated 5

Gen-ID: 51208

NCBI Accession: NP_001002026

UniProt: P56856

Pathways: Cell-Cell Junction Organization, Hepatitis C