PAX8 Antikörper (FITC)

Produktnummer ABIN673306

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PAX8 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund und Rind (Kuh).

Kurzübersicht für PAX8 Antikörper (FITC) (ABIN673306)

Target: PAX8 (Paired Box 8 (PAX8))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX8 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PAX8 Antikörper (FITC)

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse PAX8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PAX8

Target: PAX8 (Paired Box 8 (PAX8))

Andere Bezeichnung: PAX8

Hintergrund:

Synonyms: Paired Box Gene 8, paired box homeotic gene 8, Paired box protein Pax 8, Paired Domain Gene 8, PAX 8,PAX-8,

Background: This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.

Molekulargewicht: 50kDa

Gen-ID: 18510

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation