Lipin 1 Antikörper (AA 241-340)

Produktnummer ABIN672846

Dieses Anti-Lipin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Lipin 1 in IF (cc), IF (p), ELISA, IHC (p) und IHC (fro). Geeignet für Ratte und Maus.

Kurzübersicht für Lipin 1 Antikörper (AA 241-340) (ABIN672846)

Target: Lipin 1 (LPIN1)

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lipin 1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Lipin 1 Antikörper

Bindungsspezifität: AA 241-340

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Lpin 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Lipin 1

Target: Lipin 1 (LPIN1)

Andere Bezeichnung: Lpin1

Hintergrund:

Synonyms: fld, Lipin1, Kiaa0188, mKIAA0188, 4631420P06, Phosphatidate phosphatase LPIN1, Fatty liver dystrophy protein, Lipin-1, Lpin1

Background: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.

Gen-ID: 14245

UniProt: Q91ZP3

Pathways: Monocarboxylic Acid Catabolic Process