Neuropilin 1 Antikörper (AA 851-923) (Cy3)
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- Target Alle Neuropilin 1 (NRP1) Antikörper anzeigen
- Neuropilin 1 (NRP1)
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Bindungsspezifität
- AA 851-923
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Neuropilin 1 Antikörper ist konjugiert mit Cy3
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Ratte
- Homologie
- Mouse,Sheep,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human neuropilin-1
- Isotyp
- IgG
- Top Product
- Discover our top product NRP1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Neuropilin 1 (NRP1)
- Andere Bezeichnung
- Neuropilin 1 (NRP1 Produkte)
- Synonyme
- NRP1 antikoerper, cd304 antikoerper, neuropilin antikoerper, np-1 antikoerper, npn-1 antikoerper, nrp antikoerper, nrp-1 antikoerper, vegf165r antikoerper, BDCA4 antikoerper, CD304 antikoerper, NP1 antikoerper, NRP antikoerper, VEGF165R antikoerper, C530029I03 antikoerper, NP-1 antikoerper, NPN-1 antikoerper, Npn1 antikoerper, Nrp antikoerper, neuropilin 1 antikoerper, neuropilin 1 L homeolog antikoerper, NRP1 antikoerper, nrp1 antikoerper, Nrp1 antikoerper, nrp1.L antikoerper
- Hintergrund
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Synonyms: NP1, NRP, BDCA4, CD304, VEGF165R, Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, NRP1
Background: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
- Gen-ID
- 8829
- UniProt
- O14786
- Pathways
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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