LONP1 Antikörper (AA 137-320)

Produktnummer ABIN6719543

Produktdetails anti-LONP1 Antikörper

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Bindungsspezifität: AA 137-320

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LONP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for LONP1/Lon detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for LONP1/Lon detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LONP1/Lon recombinant protein (Position: R137-A320).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Kommentare:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Andere Bezeichnung: LONP1 (LONP1 Produkte)

Synonyme: PRSS15 antikoerper, prss15 antikoerper, fc64d11 antikoerper, wu:fc64d11 antikoerper, LON antikoerper, LONP antikoerper, LonHS antikoerper, PIM1 antikoerper, hLON antikoerper, 1200017E13Rik antikoerper, Prss15 antikoerper, Lon antikoerper, lon peptidase 1, mitochondrial antikoerper, ATP-dependent Lon protease antikoerper, LONP1 antikoerper, lonp1 antikoerper, Lonp1 antikoerper, PIM1 antikoerper

Hintergrund:

Synonyms: Lon protease homolog, mitochondrial, LONHs, Lon protease-like protein, LONP, Mitochondrial ATP-dependent protease Lon, Serine protease 15, LONP1, PRSS15

Background: Lon protease homolog, mitochondrial is an enzyme that in humans is encoded by the LONP1 gene. It is mapped to 19p13.3. This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia.

Gen-ID: 9361

UniProt: P36776