INPPL1 Antikörper (AA 1172-1258)

Produktnummer ABIN6719492

Produktdetails anti-INPPL1 Antikörper

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Bindungsspezifität: AA 1172-1258

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INPPL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for INPPL1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for INPPL1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human INPPL1 recombinant protein (Position: R1172-K1258).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Kommentare:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu INPPL1

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Andere Bezeichnung: INPPL1 (INPPL1 Produkte)

Synonyme: OPSMD antikoerper, SHIP2 antikoerper, 51C antikoerper, Ship2 antikoerper, inppl1 antikoerper, si:bz46j2.7 antikoerper, si:rp71-46j2.7 antikoerper, INPPL1 antikoerper, fc58a04 antikoerper, wu:fc58a04 antikoerper, zgc:198309 antikoerper, inositol polyphosphate phosphatase like 1 antikoerper, inositol polyphosphate phosphatase-like 1 antikoerper, inositol polyphosphate phosphatase-like 1b antikoerper, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B antikoerper, inositol polyphosphate phosphatase-like 1a antikoerper, INPPL1 antikoerper, Inppl1 antikoerper, inppl1b antikoerper, LOC100180571 antikoerper, inppl1a antikoerper

Hintergrund:

Synonyms: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, Protein 51C, SH2 domain-containing inositol 5'-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2, INPPL1, SHIP2

Background: SH2-domain containing Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 is an enzyme that in humans is encoded by the INPPL1 gene. The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

Gen-ID: 3636

UniProt: O15357

Pathways: Platelet-derived growth Factor Receptor Signaling