NPBWR1 Antikörper (AA 58-328)

Produktnummer ABIN6719427

Produktdetails anti-NPBWR1 Antikörper

Target: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Bindungsspezifität: AA 58-328

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPBWR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit IgG polyclonal antibody for GPCR GPR7/NPBWR1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for GPCR GPR7/NPBWR1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GPCR GPR7/NPBWR1 recombinant protein (Position: V58-A328).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Western blot|0.1-0.5 μg/mL Direct ELISA|0.1-0.5 μg/mL

Kommentare:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu NPBWR1

Target: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Andere Bezeichnung: NPBWR1 (NPBWR1 Produkte)

Synonyme: NPBWR1 antikoerper, GPR7 antikoerper, Gpr7 antikoerper, Nbpwr1 antikoerper, neuropeptides B/W receptor 1 antikoerper, neuropeptides B and W receptor 1 antikoerper, NPBWR1 antikoerper, Npbwr1 antikoerper

Hintergrund:

Synonyms: Neuropeptides B/W receptor type 1, G-protein coupled receptor 7, NPBWR1, GPR7

Background: Neuropeptides B/W receptor 1, also known as NPBW1 and GPR7, is a human protein encoded by the NPBWR1 gene. In rodent models, NPBWR1 is over-expressed in Schwann cells associated with neuropathic pain, suggesting it inhibits inflammatory pain responses. Mice without NPBW1 exhibited a stronger hostile reaction to intruders, suggesting NPBW1 has a role in stress responses.  Early studies indicated that NPB and NPW had a complex effect on appetite, but generally led to anorexia.[12] Similarly, male rats lacking NPBWR1 exhibited hyperphagiaand adult-onset obesity, though why female rats are unaffected is unknown. Researchers speculated that activating these pathways might decrease obesity, and synthesized a small-molecule ligand that is capable of stimulating both receptors at low concentrations.

Gen-ID: 2831

UniProt: P48145