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SLC34A2 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SLC34A2 in WB, ICC und IF. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.
Produktnummer ABIN6719419

Kurzübersicht für SLC34A2 Antikörper (ABIN6719419)

Target

Alle SLC34A2 Antikörper anzeigen
SLC34A2 (Solute Carrier Family 34 (Sodium Phosphate), Member 2 (SLC34A2))

Reaktivität

Human, Ratte, Maus

Wirt

  • 23
  • 1
  • 1
Kaninchen

Klonalität

  • 23
  • 2
Polyklonal

Konjugat

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SLC34A2 Antikörper ist unkonjugiert

Applikation

  • 15
  • 11
  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Verwendungszweck

    Anti-SLC34A2 Antibody Picoband®

    Sequenz

    QNWTMKNVTY KENIAKCQHI FVNFHLPDLA

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-SLC34A2 Antibody Picoband® (ABIN6719419). Tested in IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence in the middle region of human SLC34A2, which shares 83.3% amino acid (aa) sequence identity with both mouse and rat SLC34A2.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunocytochemistry/Immunofluorescence, 2 μg/mL
    1. Corut, A., Senyigit, A., Ugur, S. A., Altin, S., Ozcelik, U., Calisir, H., Yildirim, Z., Gocmen, A., Tolun, A. Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis. Am. J. Hum. Genet. 79: 650-656, 2006. 2. Feild, J. A., Zhang, L., Brun, K. A., Brooks, D. P., Edwards, R. M. Cloning and functional characterization of a sodium-dependent phosphate transporter expressed in human lung and small intestine. Biochem. Biophys. Res. Commun. 258: 578-582, 1999.

    Kommentare

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    SLC34A2 (Solute Carrier Family 34 (Sodium Phosphate), Member 2 (SLC34A2))

    Andere Bezeichnung

    SLC34A2

    Hintergrund

    Synonyms: Sodium-dependent phosphate transport protein 2B, Sodium-phosphate transport protein 2B, Na (+)-dependent phosphate cotransporter 2B, NaPi3b, Sodium/phosphate cotransporter 2B, Na (+)/Pi cotransporter 2B, NaPi-2b, Solute carrier family 34 member 2, SLC34A2

    Tissue Specificity: Highly expressed in lung. Also detected in pancreas, kidney, small intestine, ovary, testis, prostate and mammary gland. In lung, it is found in alveolar type II cells but not in bronchiolar epithelium.

    Background: Sodium-dependent phosphate transport protein 2B (NaPi2b) is a protein that in humans is encoded by the SLC34A2 gene. The protein encoded by this gene is a pH -sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH . Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene.

    Molekulargewicht

    76-130 kDa

    Gen-ID

    10568

    UniProt

    O95436
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