FABP2 Antikörper (AA 2-132)

Produktnummer ABIN6719408

Der Kaninchen Polyklonal Anti-FABP2-Antikörper wurde für ELISA validiert. Er ist geeignet, FABP2 in Proben von Maus zu detektieren.

Kurzübersicht für FABP2 Antikörper (AA 2-132) (ABIN6719408)

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FABP2 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-FABP2 Antikörper

Bindungsspezifität: AA 2-132

Verwendungszweck: Anti-FABP2/I-FABP Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-FABP2/I-FABP Antibody Picoband® (ABIN6719408). Tested in ELISA applications. This antibody reacts with Mouse.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse FABP2/I-FABP recombinant protein (Position: A2-E132).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA Capture (Matched Antibody Pair), 2-8 μg/mL1. Baier, L. J., Sacchettini, J. C., Knowler, W. C., Eads, J., Paolisso, G., Tataranni, P. A., Mochizuki, H., Bennett, P. H., Bogardus, C., Prochazka, M.An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance.J. Clin. Invest. 95: 1281-1287, 1995. 2. Georgopoulos, A., Aras, O., Tsai, M. Y.Codon-54 polymorphism of the fatty acid-binding protein 2 gene is associated with elevation of fasting and postprandial triglyceride in type 2 diabetes.J. Clin. Endocr. Metab. 85: 3155-3160, 2000. 3. Sparkes, R. S., Mohandas, T., Heinzmann, C., Gordon, J. I., Klisak, I., Zollman, S., Sweetser, D. A., Ragunathan, L., Winokur, S., Lusis, A. J.Human fatty acid binding protein assignments intestinal to 4q28-4q31 and liver to 2p11. (Abstract)Cytogenet. Cell Genet. 46: 697 only, 1987.

Kommentare:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu FABP2

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Andere Bezeichnung: Fabp2

Hintergrund:

Synonyms: Fatty acid-binding protein, intestinal,Fatty acid-binding protein 2,Intestinal-type fatty acid-binding protein,I-FABP,Fabp2,Fabpi,

Tissue Specificity: Expressed in the small intestine. Highest expression levels in the proximal ileum. .

Background: FABP 2, Fatty acid-binding protein 2, is a protein that in humans is encoded by the FABP2 gene. Using a human cDNA probe, the gene is assigned to chromosome 4 in somatic cell hybrids. FABP 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. The FABPs belong to a multigene family with nearly twenty identified members. And FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. Also, they may be responsible in the modulation of cell growth and proliferation.

Molekulargewicht: 15 kDa

Gen-ID: 14079

UniProt: P55050