Lamin B Receptor Antikörper (AA 102-209)

Produktnummer ABIN6719340

Produktdetails anti-Lamin B Receptor Antikörper

Target: Lamin B Receptor (LBR)

Bindungsspezifität: AA 102-209

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Lamin B Receptor/LBR detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Lamin B Receptor/LBR detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Lamin B Receptor/LBR recombinant protein (Position: H102-F209).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Kommentare:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Lamin B Receptor

Target: Lamin B Receptor (LBR)

Andere Bezeichnung: LBR (LBR Produkte)

Synonyme: CG17952 antikoerper, Dmel\\CG17952 antikoerper, dLBR antikoerper, sb:cb406 antikoerper, zgc:86649 antikoerper, wu:fb75h08 antikoerper, wu:fc47b04 antikoerper, wu:fd36b07 antikoerper, lbr-A antikoerper, Xp58 antikoerper, p58 gene antikoerper, LBR antikoerper, DHCR14B antikoerper, LMN2R antikoerper, PHA antikoerper, TDRD18 antikoerper, AI505894 antikoerper, ic antikoerper, Nbp60 antikoerper, lamin B receptor antikoerper, Lamin B receptor antikoerper, lamin B receptor S homeolog antikoerper, LBR antikoerper, lbr antikoerper, lbr.S antikoerper, Lbr antikoerper

Hintergrund:

Synonyms: Lamin-B receptor, Integral nuclear envelope inner membrane protein, LMN2R, LBR

Background: Lamin-B receptor is a protein, and in humans, it is encoded by the LBR gene. It is mapped to 1q42.12. The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Gen-ID: 3930

UniProt: Q14739