MVP Antikörper (AA 88-180)

Produktnummer ABIN671586

Dieses Anti-MVP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MVP in FACS, ELISA, IHC (p), IHC (fro), IF (cc) und IF (p). Geeignet für Human und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für MVP Antikörper (AA 88-180) (ABIN671586)

Target: MVP (Major Vault Protein (MVP))

Reaktivität: Human, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MVP Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MVP Antikörper

Bindungsspezifität: AA 88-180

Kreuzreaktivität: Human, Zebrafisch (Danio rerio)

Kreuzreaktivität (Details): Zebrafish

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-MVP Antikörper (ABIN671586)

Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

Pan, Lin, Ma, Shen, Schachner: "Major vault protein promotes locomotor recovery and regeneration after spinal cord injury in adult zebrafish." in: The European journal of neuroscience, Vol. 37, Issue 2, pp. 203-11, (2013) (PubMed).

Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

Details zu MVP

Target: MVP (Major Vault Protein (MVP))

Andere Bezeichnung: LRP

Hintergrund:

Synonyms: LRP, VAULT1, Major vault protein, MVP, Lung resistance-related protein

Background: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Gen-ID: 9961

UniProt: Q14764