Adiponectin Receptor 2 Antikörper (AA 315-340)

Produktnummer ABIN670851

Dieses Anti-Adiponectin Receptor 2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Adiponectin Receptor 2 in WB, ELISA, FACS, IF (cc), IF (p), IHC (fro) und IHC (p). Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für Adiponectin Receptor 2 Antikörper (AA 315-340) (ABIN670851)

Target: Adiponectin Receptor 2 (ADIPOR2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adiponectin Receptor 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Adiponectin Receptor 2 Antikörper

Bindungsspezifität: AA 315-340

Spezifität: This antibody may cross react with Adiponectin receptor 1 due to sequence similarity.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adiponectin receptor 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Adiponectin Receptor 2 Antikörper (ABIN670851)

Morad, Abrahamsson, Dabrosin: "Estradiol affects extracellular leptin:adiponectin ratio in human breast tissue in vivo." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. 3460-7, (2014) (PubMed).

Ji, Wu, Ma, Ma, Qin: "The effect of resveratrol on the expression of AdipoR1 in kidneys of diabetic nephropathy." in: Molecular biology reports, Vol. 41, Issue 4, pp. 2151-9, (2014) (PubMed).

Guo, Qin, Zhang, Li, Yin: "Effect of rosiglitazone on the expression of cardiac adiponectin receptors and NADPH oxidase in type 2 diabetic rats." in: European journal of pharmacology, Vol. 685, Issue 1-3, pp. 116-25, (2012) (PubMed).

Liu, Wu, Zhang, Chen, Liu, Wu, Zhu: "The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis is associated with regulating adiponectin receptor expression in rats." in: European journal of pharmacology, Vol. 650, Issue 1, pp. 384-9, (2010) (PubMed).

Details zu Adiponectin Receptor 2

Target: Adiponectin Receptor 2 (ADIPOR2)

Andere Bezeichnung: Adiponectin receptor 2

Hintergrund:

Synonyms: PAQR2, ACDCR2, Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2

Background: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.

Gen-ID: 79602

UniProt: Q86V24

Pathways: AMPK Signaling