SPINT1 Antikörper (AA 451-529) (Biotin)

Produktnummer ABIN669863

Der Kaninchen Polyklonal anti-SPINT1 Antikörper wird verwendet zum Nachweis von SPINT1 in Proben von Maus. Er wurde validiert für WB, ELISA, IHC (p) und IHC (fro).

Kurzübersicht für SPINT1 Antikörper (AA 451-529) (Biotin) (ABIN669863)

Target: SPINT1 (serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPINT1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-SPINT1 Antikörper (Biotin)

Bindungsspezifität: AA 451-529

Kreuzreaktivität: Maus

Homologie: Human,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HAI-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SPINT1

Target: SPINT1 (serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1))

Andere Bezeichnung: HAI-1

Hintergrund:

Synonyms: Hepatocyte Growth Factor Activator Inhibitor 1, Spint1, Hai1, HGFA Inhibitor 1, HAI-1, SPIT1_HUMAN.

Background: HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence.

Gen-ID: 6692