SOX2 Antikörper (AA 227-317) (Cy5)

Produktnummer ABIN669625

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SOX2 in WB, FACS, IF (p) und IF (cc). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Ziege und wurde in 1 Publikation erwähnt.

Kurzübersicht für SOX2 Antikörper (AA 227-317) (Cy5) (ABIN669625)

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reaktivität: Human, Maus, Ratte, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX2 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-SOX2 Antikörper (Cy5)

Bindungsspezifität: AA 227-317

Kreuzreaktivität: Ziege, Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Transcription factor SOX-2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SOX2 Antikörper (Cy5) (ABIN669625)

Vadasz, Jensen, Moncada, Girard, Zhang, Blanchette, Finck: "Second and third trimester amniotic fluid mesenchymal stem cells can repopulate a de-cellularized lung scaffold and express lung markers." in: Journal of pediatric surgery, Vol. 49, Issue 11, pp. 1554-63, (2014) (PubMed).

Details zu SOX2

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Andere Bezeichnung: SOX2

Hintergrund:

Synonyms: lcc, ysb, Sox-2, Transcription factor SOX-2, Sox2

Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Gen-ID: 20674

UniProt: P48432

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis