PKA Antikörper (AA 17-100)

Produktnummer ABIN669576

Zitiert in 4+ Publikationen. Der Kaninchen Polyklonal anti-PKA Antikörper (ABIN669576) detektiert spezifisch PKA in WB, IF (cc), IF (p), IHC (fro) und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Rind (Kuh).

Kurzübersicht für PKA Antikörper (AA 17-100) (ABIN669576)

Target: PKA (Protein Kinase A (PKA))

Reaktivität: Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PKA Antikörper

Bindungsspezifität: AA 17-100

Verwendungszweck: PKA alpha + beta Polyclonal Antibody

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from bovine PKA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PKA Antikörper (ABIN669576)

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Zhou, Tanaka, Matsunaga, Iseki, Watanabe, Matsuki, Ikegaya, Koyama: "Photoactivated adenylyl cyclase (PAC) reveals novel mechanisms underlying cAMP-dependent axonal morphogenesis." in: Scientific reports, Vol. 5, pp. 19679, (2016) (PubMed).

Yao, Yue, Yun, Sang: "Chronic SO2 inhalation above environmental standard impairs neuronal behavior and represses glutamate receptor gene expression and memory-related kinase activation via neuroinflammation in rats." in: Environmental research, Vol. 137, pp. 85-93, (2015) (PubMed).

Haolong, Du, Hongchao, Yang, Wei, Hua, Wenliang, Lei, Po: "Enterovirus 71 VP1 activates calmodulin-dependent protein kinase II and results in the rearrangement of vimentin in human astrocyte cells." in: PLoS ONE, Vol. 8, Issue 9, pp. e73900, (2013) (PubMed).

Details zu PKA

Target: PKA (Protein Kinase A (PKA))

Andere Bezeichnung: PKA alpha + beta

Hintergrund:

Synonyms: cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta, PRKACB

Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, and differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (By similarity).

Gen-ID: 282323

UniProt: P05131

Pathways: SARS-CoV-2 Protein Interaktom