RGS2 Antikörper (AA 116-211) (Biotin)

Produktnummer ABIN669293

This anti-RGS2 antibody (ABIN669293) is a Rabbit Polyclonal antibody detecting RGS2 in ELISA, IHC (p), IHC (fro). Suitable for Human, Rat.

Quick Overview for RGS2 Antikörper (AA 116-211) (Biotin) (ABIN669293)

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-RGS2 Antikörper (Biotin)

Bindungsspezifität: AA 116-211

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RGS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu RGS2

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Andere Bezeichnung: RGS2

Hintergrund:

Synonyms: GS8, Regulator of G-protein signaling 2, RGS2, Cell growth-inhibiting gene 31 protein, G/G1 switch regulatory protein 8, GIG31

Background: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.

Gen-ID: 5997

UniProt: P41220

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation