ITGB1 Antikörper (AA 25-100)

Produktnummer ABIN669216

Dieses Anti-ITGB1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ITGB1 in WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc) und IF (p). Geeignet für Human, Maus, Ratte, Schaf und Kaninchen. Dieses Primary Antibody wurde in 10+ Publikationen zitiert.

Kurzübersicht für ITGB1 Antikörper (AA 25-100) (ABIN669216)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Reaktivität: Human, Maus, Ratte, Schaf, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ITGB1 Antikörper

Bindungsspezifität: AA 25-100

Kreuzreaktivität: Human, Maus, Kaninchen, Ratte, Schaf

Homologie: Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin beta 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ITGB1 Antikörper (ABIN669216)

Ji, Zhang, Zhang, Fan, Liu, Yang, Hu, Liu, Dong: "MicroRNA 143-5p regulates alpaca melanocyte migration, proliferation and melanogenesis." in: Experimental dermatology, Vol. 27, Issue 2, pp. 166-171, (2018) (PubMed).

Zhao, Yu, Yang, Xue, Liu, Jin: "Knockdown of Snail inhibits epithelial-mesenchymal transition of human laryngeal squamous cell carcinoma Hep-2 cells through the vitamin D receptor signaling pathway." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 95, Issue 6, pp. 672-678, (2017) (PubMed).

Qin, Wang, Zheng, Zhou, Zhang, Yang, Zhou: "Concentrated growth factor promotes Schwann cell migration partly through the integrin β1-mediated activation of the focal adhesion kinase pathway." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1363-70, (2016) (PubMed).

Wang, Huang, Tang, Lin, Zhou: "Effects of panax notoginseng saponins on the osteogenic differentiation of rabbit bone mesenchymal stem cells through TGF-β1 signaling pathway." in: BMC complementary and alternative medicine, Vol. 16, Issue 1, pp. 319, (2016) (PubMed).

Oralova, Matalova, Killinger, Knopfova, Smarda, Buchtova: "Osteogenic Potential of the Transcription Factor c-MYB." in: Calcified tissue international, Vol. 100, Issue 3, pp. 311-322, (2016) (PubMed).

Fu, Song, Wen, Lu, Cui: "Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice." in: Nutrients, Vol. 8, Issue 5, (2016) (PubMed).

Deng, Chen, Li, Yuan, Li, Ke, Wang, Wu, Luo: "Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 10555-64, (2015) (PubMed).

Jiang, Wang, Zhang, Tang, Ren, Chen: "The role of CD29-ILK-Akt signaling-mediated epithelial-mesenchymal transition of liver epithelial cells and chemoresistance and radioresistance in hepatocellular carcinoma cells." in: Medical oncology (Northwood, London, England), Vol. 32, Issue 5, pp. 141, (2015) (PubMed).

Lei, Guo, Qiu, Lai, Yang, Widelitz, Chuong, Lian, Yang: "Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration." in: Experimental dermatology, Vol. 23, Issue 6, pp. 407-13, (2014) (PubMed).

Chen, Shi, Shu, Xie, Yang, Zhang, Ruan, Lin, Lin, Shen, Zhang, Feng, Xie: "The effect of porcine ADM to improve the burn wound healing." in: International journal of clinical and experimental pathology, Vol. 6, Issue 11, pp. 2280-91, (2013) (PubMed).

Details zu ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Andere Bezeichnung: Integrin beta 1

Hintergrund:

Synonyms: CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, VLA-4 subunit beta, ITGB1

Background: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Gen-ID: 3688

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom