TXN Antikörper (AA 51-105)

Produktnummer ABIN668871

Dieses Anti-TXN-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TXN in WB, ELISA, IHC (p), IHC (fro), IF (cc) und IF (p). Geeignet für Human, Ratte und Maus. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für TXN Antikörper (AA 51-105) (ABIN668871)

Target: TXN (Thioredoxin (TXN))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TXN Antikörper

Bindungsspezifität: AA 51-105

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Thioredoxin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-TXN Antikörper (ABIN668871)

Zhang, Hu, Guo, Wang, Zhao, Zhang, Yang, Yu, Niu, Yang, Zheng, Wang: "Screening and identification of post-traumatic stress-related serum factors in children with Wilms' tumors." in: Oncology letters, Vol. 11, Issue 2, pp. 1299-1304, (2016) (PubMed).

Gao, Yuan, Gao, Cai, Zhu, Liu, Wang, Wei, Huang, Liang, Gao: "Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles." in: Biomaterials, Vol. 35, Issue 31, pp. 8854-66, (2014) (PubMed).

Li, Sun, Xiao, Sun: "First characterization of a teleost Epstein-Barr virus-induced gene 3 (EBI3) reveals a regulatory effect of EBI3 on the innate immune response of peripheral blood leukocytes." in: Developmental and comparative immunology, Vol. 41, Issue 4, pp. 514-22, (2013) (PubMed).

Details zu TXN

Target: TXN (Thioredoxin (TXN))

Andere Bezeichnung: Thioredoxin

Hintergrund:

Synonyms: TRX, TRDX, TRX1, Thioredoxin, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP, TXN

Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).

Gen-ID: 7295

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis