Synaptojanin 1 Antikörper (C-Term)
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- Target Alle Synaptojanin 1 (SYNJ1) Antikörper anzeigen
- Synaptojanin 1 (SYNJ1)
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Bindungsspezifität
- C-Term
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Reaktivität
- Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Synaptojanin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Kreuzreaktivität (Details)
- Cross reactivity from other species has not been determined.
- Aufreinigung
- Anti-Synaptojanin 1 Monoclonal Antibody is directed against rat synaptojanin 1. Synaptojanin 1 antibody was Protein G purified. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody.
- Immunogen
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Immunogen: Anti-Synaptojanin 1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant protein from the C-terminal region of rat synaptojanin 1.
Immunogen Type: Recombinant Protein
- Klon
- 5H1
- Isotyp
- IgG
- Top Product
- Discover our top product SYNJ1 Primärantikörper
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- Applikationshinweise
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Immunohistochemistry Dilution: 1:100
Application Note: Anti-Synaptojanin 1 antibody is suitable for use in Western Blotting and IHC. Expect a band of approximately 145 kDa in size corresponding to synaptojanin I proteins of rat brain extracts. Researchers should determine optimal titers for applications that are not stated below.
Western Blot Dilution: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- Target
- Synaptojanin 1 (SYNJ1)
- Andere Bezeichnung
- Synaptojanin 1 (SYNJ1 Produkte)
- Synonyme
- CG6562 antikoerper, Dmel\\CG6562 antikoerper, IPP antikoerper, Synj antikoerper, fb02f11 antikoerper, fi15a11 antikoerper, nrc antikoerper, wu:fb02f11 antikoerper, wu:fi15a11 antikoerper, SYNJ1 antikoerper, INPP5G antikoerper, A930006D20Rik antikoerper, AA675315 antikoerper, mKIAA0910 antikoerper, Synaptojanin antikoerper, synaptojanin 1 antikoerper, Synj antikoerper, synj1 antikoerper, SYNJ1 antikoerper, Synj1 antikoerper
- Hintergrund
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Synonyms: mouse anti-Synaptojanin 1 Antibody, Synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1
Background: Synaptojanin 1 Monoclonal Antibody detects Synaptojanin 1, which is a phosphatidylinositol phosphatase involved in clathrin-mediated endocytosis of synaptic vesicles. Synaptojanin 1 has two alternatively spliced isoforms, one that is ~ 145 kDA and is exclusively expressed in neurons, and the other ~ 170 kDa which is expressed in non-neuronal, peripheral tissues. The gene which encodes Synaptojanin 1, SYNJ1, has been mapped to chromosome 21 thus making it a candidate for involvement in Down's syndrome (DS). It has recently been demonstrated that Ts65Dn mice (the most commonly used model of DS) have altered phosphatidylinositol-4,5-bisphosphate metabolism. This defect is rescued by restoring SYNJ1 to disomy in the Ts65Dn mice.
Gene Name: SYNJ1
- Gen-ID
- 85238
- UniProt
- Q62910
- Pathways
- Inositol Metabolic Process, Synaptic Vesicle Exocytosis
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