STXBP2 Antikörper (pSer515)

Produktnummer ABIN6658248

Hersteller Produkt- Nr.: 600-401-x16

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STXBP2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für STXBP2 Antikörper (pSer515) (ABIN6658248)

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STXBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-STXBP2 Antikörper

Bindungsspezifität: pSer515

Hersteller Produkt- Nr.: 600-401-x16

Hersteller: Rockland

Verwendungszweck: Munc18 Phospho S515 Antibody

Kreuzreaktivität (Details): Anti-Phospho-Ser515 Munc18 Antibody is directed against Munc18 protein phosphorylated at S515.

Aufreinigung: The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.

Sterilität: Sterile filtered

Immunogen: Anti-Phospho-Ser515 Munc18 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser515 of rat Munc18 conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-Phospho-Ser515 Munc18 Antibody is tested for Western Blot, and it is specific for the ~65 kDa Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Preservative: None

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.

Haltbarkeit: 12 months

Details zu STXBP2

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Andere Bezeichnung: Stxbp2

Hintergrund:

Synonyms: Syntaxin-binding protein 2, Protein unc-18 homolog 2, Unc18-2, Protein unc-18 homolog B, Unc-18B

Background: Munc-18 ( mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin. Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex. The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein. Munc-18 pS515 Antibody is ideal for researchers interested in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: STXBP2

Gen-ID: 81804

NCBI Accession: NP_112388

UniProt: Q62753

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis