GABBR1 Antikörper (pSer923)

Produktnummer ABIN6658230

Hersteller Produkt- Nr.: 612-401-d54

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GABBR1 in WB. Er zeigt eine Reaktivität gegenüber Ratte und wurde in 1 Publikation erwähnt.

Kurzübersicht für GABBR1 Antikörper (pSer923) (ABIN6658230)

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GABBR1 Antikörper

Bindungsspezifität: pSer923

Hersteller Produkt- Nr.: 612-401-d54

Hersteller: Rockland

Verwendungszweck: GABA(B) Receptor 1 phospho S923 Antibody

Kreuzreaktivität (Details): Anti-GABA(B) Receptor 1 pS923 Antibody is directed against rat phosphorylated GABA(B) Receptor .

Aufreinigung: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-GABA(B) Receptor 1 pS923 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 923 of rat GABA B R1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1:1000

Kommentare:

Anti-GABA(B) Receptor 1 pS923 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 102 kDa in size corresponding to GABA(B) receptor 1 protein phosphorylated at Ser923 in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Referenzen für anti-GABBR1 Antikörper (ABIN6658230)

Feng, Gao, Yue, Liu, Zhou, Ren, Teng: "Autophagy-lysosome dysfunction is involved in gastric ischemia-reperfusion injury by promoting microglial activation in the paraventricular nucleus." in: Journal of biochemical and molecular toxicology, Vol. 36, Issue 2, pp. e22957, (2022) (PubMed).

Details zu GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Andere Bezeichnung: GABA(B) Receptor 1

Hintergrund:

Synonyms: Gamma-aminobutyric acid type B receptor subunit 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1

Background: GABA(A) Receptor 1 pS923 Antibody detects phosphorylated GABA(A) Receptor gamma 2. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling. Phosphorylation of Ser 923 is thought to be important in the regulation of GABAB receptor function. GABA(B) Receptor 1 pS923 antibody is ideal for investigators involved in Neuroscience.

Gene Name: GABBR1

Gen-ID: 81657, 8393403

UniProt: Q9Z0U4

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process