Neuroligin 1 Antikörper (AA 718-843)

Produktnummer ABIN6658164

Hersteller Produkt- Nr.: 200-301-w75

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Neuroligin 1 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für Neuroligin 1 Antikörper (AA 718-843) (ABIN6658164)

Target: Neuroligin 1 (NLGN1)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuroligin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: S97A-31

Produktdetails anti-Neuroligin 1 Antikörper

Bindungsspezifität: AA 718-843

Hersteller Produkt- Nr.: 200-301-w75

Hersteller: Rockland

Verwendungszweck: Neuroligin 1 Antibody

Kreuzreaktivität (Details): BLAST analysis suggests that it is 99 % identical to mouse, 99 % identical to human and >50 % identical to Neuroligin-2 and -3.

Aufreinigung: Anti-Neuroligin 1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Sterilität: Sterile filtered

Immunogen: Anti-Neuroligin 1 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 718-843 of rat Neuroligin-1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:5,000

Immunohistochemistry_Dilution: User Optimized

Western_Blot_Dilution: 1:500

Kommentare:

Anti-Neuroligin 1 Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~120kDa on specific lysates or tissues. Does not cross react with other Neuroligins. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Neuroligin 1

Target: Neuroligin 1 (NLGN1)

Andere Bezeichnung: Neuroligin 1

Hintergrund:

Synonyms: NLG 1, KIAA1070, MGC45115, Neuroligin-1, NL1, NLG1, Nlgn1

Background: Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord. Anti-Neuroligin-1 is ideal for research in Neuroscience, including narcolepsy and synaptic neurotransmission: GABAergic inhibition, as well as Cell Adhesion.

Gene Name: Neuroligin-1

Gen-ID: 116647

UniProt: Q62765

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis