GAP43 Antikörper (pSer41)

Produktnummer ABIN6658158

Hersteller Produkt- Nr.: 612-401-d59

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GAP43 in WB. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für GAP43 Antikörper (pSer41) (ABIN6658158)

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAP43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GAP43 Antikörper

Bindungsspezifität: pSer41

Hersteller Produkt- Nr.: 612-401-d59

Hersteller: Rockland

Verwendungszweck: Neuromodulin phospho S41 Antibody

Kreuzreaktivität (Details): This antibody is specific for the phosphorylated forms of the protein.

Aufreinigung: Anti-GAP43 pS41 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-Neuromodulin Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser41 of GAP43.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western_Blot_Dilution: 1:1000

Other: User Optimized

Kommentare:

Anti-GAP43 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 50 kDa in size corresponding to neuromodulin protein phosphorylated at Ser41 in the appropriate cell lysate or extract. In some tissues, the antibody also recognized a higher molecular weight protein that may be an aggregate or oligomer.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu GAP43

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Andere Bezeichnung: Neuromodulin (GAP43)

Hintergrund:

Synonyms: Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43, Protein F1, Neural phosphoprotein B-50, pp46

Background: Gap-43 pS41 antibody detects phophorylated GAP43 at position S41. Gap43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that Gap-43 serves to amplify pathfinding signals from the growth cone. Gap-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser41 by protein kinase C modulates the interaction of Gap-43 with actin and may also affect eurotransmitter release during forms of plasticity like LTP. Anti-Gap-43 pS41 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Signal Transduction research.

Gene Name: GAP43

Gen-ID: 29423

UniProt: P07936