GRIN2B Antikörper (N-Term)

Produktnummer ABIN6658131

Hersteller Produkt- Nr.: 200-301-g23

Dieses Maus Monoklonal-Antikörper erkennt spezifisch GRIN2B in WB, IHC, IP, IF und FM. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für GRIN2B Antikörper (N-Term) (ABIN6658131)

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GRIN2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Klon: S59-36

Produktdetails anti-GRIN2B Antikörper

Bindungsspezifität: N-Term

Hersteller Produkt- Nr.: 200-301-g23

Hersteller: Rockland

Verwendungszweck: NR2B Antibody

Kreuzreaktivität (Details): A BLAST analysis was used to suggest cross-reactivity with NR2B from human, mouse, and rat based on 100 % homology with the immunizing sequence.

Aufreinigung: Anti-NR2B Antibody was purified by Protein G chromatography.

Sterilität: Sterile filtered

Immunogen: NR2B Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding near the extracellular N-terminus region of rat NR2B.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

IF_Microscopy_Dilution: 1.0-10 μg/mL

Western_Blot_Dilution: 1-10 μg/mL

Kommentare:

Anti-NR2B Antibody is tested for use in WB, IHC, IF, and IP. Expect a band approximately ~166kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Andere Bezeichnung: NR2B

Hintergrund:

Synonyms: NMDAR2B, hNR3, MGC142180, glutamate receptor subunit epsilon-2, NR3, NR2B, N-methyl D-aspartate receptor subtype 2B

Background: NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation. Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain, NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics.

Gene Name: Grin2b

Gen-ID: 24410

NCBI Accession: NP_036706

UniProt: Q00960

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity