GRIN2B Antikörper (C-Term)

Produktnummer ABIN6658130

Hersteller Produkt- Nr.: 100-401-c87

Dieses Anti-GRIN2B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GRIN2B in WB. Geeignet für Ratte.

Kurzübersicht für GRIN2B Antikörper (C-Term) (ABIN6658130)

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIN2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRIN2B Antikörper

Bindungsspezifität: C-Term

Hersteller Produkt- Nr.: 100-401-c87

Hersteller: Rockland

Verwendungszweck: NMDA R2B Antibody

Kreuzreaktivität (Details): Anti-NMDA R2B antibody is directed against NMDA R2Bprotein.

Aufreinigung: The antibody was prepared from monospecific neat serum.

Immunogen: Anti-NMDA R2B Antibody was produced by repeated immunizations with a fusion protein from the C-terminal region of the NR2B subunit.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1:1000

Kommentare:

Anti-NMDA R2B Antibody has been tested in Western Blotting. Expect a band of approximately 180kDa in size corresponding to the NR2B subunit of the NMDA receptor in appropriate cell lysate or extract. A dilution of 1:1000 is recommended in western blotting although specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Andere Bezeichnung: NMDA R2B

Hintergrund:

Synonyms: Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B, Grin2b

Background: NMDA R2B Antibody detects NMDA R2B protein. The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Anti-NMDA R2B Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research.

Gene Name: GRIN2B

Gen-ID: 24410

UniProt: Q00960

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity