Peripherin Antikörper

Produktnummer ABIN6658100

Hersteller Produkt- Nr.: 900-301-e11

Dieses Anti-Peripherin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Peripherin in WB, IHC und FM. Geeignet für Ratte.

Kurzübersicht für Peripherin Antikörper (ABIN6658100)

Target: Peripherin (PRPH)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Peripherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Klon: 7C5

Produktdetails anti-Peripherin Antikörper

Hersteller Produkt- Nr.: 900-301-e11

Hersteller: Rockland

Verwendungszweck: Peripherin Antibody

Kreuzreaktivität (Details): Anti-Peripherin antibody is directed against rat Peripherin.

Aufreinigung: The antibody is protein G purified from concentrated clarified cell culture supernate.

Immunogen: Anti-Peripherin Antibody (Monoclonal) was produced by repeated immunizations with recombinant rat peripherin expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

IF_Microscopy_Dilution: 1:200

Western_Blot_Dilution: 1:1000

Other: User Optimized

Kommentare:

Anti-Peripherin Antibody is tested for use in Western Blotting, ICC, and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 57 kDa in size corresponding to peripherin proteins in the appropriate cell lysate or extract. Anti-Peripherin antibody performs well on aldehyde fixed tissues.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Peripherin

Target: Peripherin (PRPH)

Andere Bezeichnung: Peripherin

Hintergrund:

Synonyms: NEF4, PRPH1, Peripherin, prph, prph1 antibody, PNS antibodies, monoclonal anti-peripherin, mouse monoclonal antibody to peripherin, monoclonal anti-peripherin antibody produced in mouse

Background: Peripherin Antibody detects Peripherin. Peripherin is a ~57 kDa intermediate filament subunit found initially in sensory neurons of the peripheral nervous systems, which gives the protein its name. Subsequently, peripherin was found in some sensory and other neurons of the central nervous system and also in PC12 cells. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Peripherin belongs to the Class III family of intermediate filament subunits which also includes vimentin, glial fibrillary acidic protein (GFAP) and desmin. In contrast to the neurofilaments, peripherin is strongly up-regulated after nerve injury. Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good diagnostic marker for ballooned axons seen in Lou Gehrig's disease (Amyotrophic lateral sclerosis) and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. Peripherin is not related to peripherin/RDS, a protein of the photoreceptor outer membrane mutations of which are causative of certain forms of slow retinal degeneration. Anti-Peripherin Antibody is ideal for investigators involved in Neuroscience and Cancer research.

Gene Name: PRPH

Gen-ID: 3414

UniProt: P21807