Neuroligin 3 Antikörper (AA 730-848)

Produktnummer ABIN6658074

Hersteller Produkt- Nr.: 200-301-w83

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Neuroligin 3 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für Neuroligin 3 Antikörper (AA 730-848) (ABIN6658074)

Target: Neuroligin 3 (NLGN3)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Neuroligin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: S110-29

Produktdetails anti-Neuroligin 3 Antikörper

Bindungsspezifität: AA 730-848

Hersteller Produkt- Nr.: 200-301-w83

Hersteller: Rockland

Verwendungszweck: Neuroligin 3 Antibody

Kreuzreaktivität (Details): BLAST analysis suggests that it is 99 % identical to mouse, 98 % identical to human, ~60 % identical with Neuroligin-1 and ~40 % identical to Neuroligin-2.

Aufreinigung: Anti-Neuroligin-3 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Sterilität: Sterile filtered

Immunogen: Anti-Neuroligin 3 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 730-848 of rat Neuroligin-3.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-Neuroligin-3 Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~110kDa on specific lysates or tissues. Does not cross react with Neuroligin -1, -2, or -4. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Neuroligin 3

Target: Neuroligin 3 (NLGN3)

Andere Bezeichnung: Neuroligin 3

Hintergrund:

Synonyms: Gliotactin homolog, Neuroligin-3, Nlgn3, NLGN3_HUMAN

Background: Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. Anti-Neuroligin-3 is ideal for research in Neuroscience, including autism research, and Cell Adhesion and Communication.

Gene Name: Neuroligin-3

Gen-ID: 171297

UniProt: Q62889

Pathways: Synaptic Membrane