LGI1 Antikörper (AA 37-113) (Biotin)

Produktnummer ABIN6657729

Hersteller Produkt- Nr.: 200-306-w73

Dieses Maus Monoklonal-Antikörper erkennt spezifisch LGI1 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für LGI1 Antikörper (AA 37-113) (Biotin) (ABIN6657729)

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LGI1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: S283-7

Produktdetails anti-LGI1 Antikörper (Biotin)

Bindungsspezifität: AA 37-113

Hersteller Produkt- Nr.: 200-306-w73

Hersteller: Rockland

Verwendungszweck: Lgi1 Antibody Biotin

Kreuzreaktivität (Details): BLAST analysis suggests that it is 100 % identical to rat, 98 % identical to human and ~50 % identical to LGI2, LGI3, and LGI4.

Aufreinigung: Anti-LGI1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Sterilität: Sterile filtered

Immunogen: Anti-LGI1 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 37-113 (LRRNT domain and first LRR repeat) of mouse LGI1.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-LGI1 Biotin Conjugated Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~60kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu LGI1

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Andere Bezeichnung: LGI1

Hintergrund:

Synonyms: ADLTE, ADPAEF, ADPEAF, Epitempin 1, EPT, ETL1, IB1099, leucine rich glioma inactivated 1, OTTHUMP00000020121, OTTHUMP00000020133

Background: The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist, this LGI1 antibody will recognize only the longer form. Anti-LGI1 is ideal for research in Neuroscience and Cancer.

Gene Name: LGI1

Gen-ID: 56839

UniProt: Q9JIA1