AHSA1 Antikörper

Produktnummer ABIN6657694

Hersteller Produkt- Nr.: 100-401-e82

Der Kaninchen Polyklonal Anti-AHSA1-Antikörper wurde für WB, ELISA, IHC und IP validiert. Er ist geeignet, AHSA1 in Proben von Maus zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für AHSA1 Antikörper (ABIN6657694)

Target: AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AHSA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-AHSA1 Antikörper

Hersteller Produkt- Nr.: 100-401-e82

Hersteller: Rockland

Verwendungszweck: Aha1 Antibody

Kreuzreaktivität (Details): A BLAST analysis was used to suggest cross-reactivity with Aha 1 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

Aufreinigung: Anti-Aha 1 Antibody was purified by Protein A chromatography.

Sterilität: Sterile filtered

Immunogen: Aha1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with Mouse Aha1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunoprecipitation_Dilution: User Optimized

ELISA_Dilution: 1:200

Immunohistochemistry_Dilution: 1:1000

Western_Blot_Dilution: 0.5-1:1000

Kommentare:

Anti-Aha1 Antibody has been tested in western blot, ICC, and IHC and is suitable for use in ELISA, IF microscopy and IP. Expect a band approximately ~38kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Referenzen für anti-AHSA1 Antikörper (ABIN6657694)

Jinwal, Koren, Dickey: "Reconstructing the Hsp90/Tau Machine." in: Current enzyme inhibition, Vol. 9, Issue 1, pp. 41-45, (2013) (PubMed).

Details zu AHSA1

Target: AHSA1 (Activator of HSP90 ATPase Activity 1 (AHSA1))

Andere Bezeichnung: Aha1

Hintergrund:

Synonyms: Aha1, SHSA1, HspC322, p38, Activator of 90 kDa heat shock protein ATPase homolog 1

Background: Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding. It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors.

Gene Name: Ahsa1

Gen-ID: 217737

NCBI Accession: NP_666148

UniProt: Q8BK64