Ataxin 1 Antikörper (AA 164-197)

Produktnummer ABIN6657649

Hersteller Produkt- Nr.: 200-301-w69

Der Maus Monoklonal Anti-Ataxin 1-Antikörper wurde für WB, IHC, ELISA, IF und IP validiert. Er ist geeignet, Ataxin 1 in Proben von Maus zu detektieren.

Kurzübersicht für Ataxin 1 Antikörper (AA 164-197) (ABIN6657649)

Target: Ataxin 1 (ATXN1)

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ataxin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: S76-8

Produktdetails anti-Ataxin 1 Antikörper

Bindungsspezifität: AA 164-197

Hersteller Produkt- Nr.: 200-301-w69

Hersteller: Rockland

Verwendungszweck: Ataxin 1 Antibody

Kreuzreaktivität (Details): BLAST analysis suggests that it is 100 % identical to rat and 88 % identical to human.

Aufreinigung: Anti-Ataxin 1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Sterilität: Sterile filtered

Immunogen: Anti-Ataxin 1 Antibody was produced by repeated immunization of mice with a synthetic peptide containing amino acids 164-197 of mouse Ataxin 1.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Immunoprecipitation_Dilution: User Optimized

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Other: ICC/IF: 1:100

Kommentare:

Anti-Ataxin 1 Antibody is tested for Western Blots, Immunohistochemistry and Immunoprecipitation. Expect a band approximately ~85 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Ataxin 1

Target: Ataxin 1 (ATXN1)

Andere Bezeichnung: Ataxin 1

Hintergrund:

Synonyms: Ataxin-1, ATX1, Atxn1, D6S504E, OTTHUMP00000016065, SCA1, Spinocerebellar ataxia type 1 protein

Background: Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons. Anti-Ataxin-1 is ideal for research in Neuroscience.

Gene Name: Ataxin 1

Gen-ID: 20238

UniProt: P54254

Pathways: Synaptic Membrane