Periostin Antikörper (C-Term)

Produktnummer ABIN6657608

Hersteller Produkt- Nr.: 600-401-e09

Dieses Anti-Periostin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Periostin in WB und IHC. Geeignet für Maus.

Kurzübersicht für Periostin Antikörper (C-Term) (ABIN6657608)

Target: Periostin (POSTN)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Periostin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Periostin Antikörper

Bindungsspezifität: C-Term

Hersteller Produkt- Nr.: 600-401-e09

Hersteller: Rockland

Verwendungszweck: Periostin Antibody

Kreuzreaktivität (Details): Anti-Periostin antibody is directed against mouse Periostin protein.

Aufreinigung: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-Periostin Antibody was produced by repeated immunizations with bacterial fusion proteins equivalent to a 188 amino acid polypeptide from the C-terminal region of mouse periostin which is comprised of six small alternatively spliced exons.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry_Dilution: 1:100

Western_Blot_Dilution: 1:1000

Other: User Optimized

Kommentare:

Anti-Periostin Antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 93 kDa in size corresponding to periostin doublet in mouse lung extract. The antibody works well for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrieval protocol (incubate slides for 20 minutes at 90° C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Periostin

Target: Periostin (POSTN)

Andere Bezeichnung: Periostin

Hintergrund:

Synonyms: PN, Osteoblast-specific factor 2, OSF-2

Background: Periostin Antibody detects Periostin protein. Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Periostin has since been demonstrated to be important in heart valve development and myocardial infarction because it promotes collagen fibrogenesis, inhibits differentiation of progenitor cells into cardiomyocytes and is essential in maintaining the biomechanical properties of the adult myocardium. Anti-Periostin Antibody is ideal for investigators involved in Cancer and Cardiovascular research.

Gene Name: POSTN

Gen-ID: 50706

UniProt: Q62009