Apelin Antikörper (C-Term)

Produktnummer ABIN6657507

Produktdetails anti-Apelin Antikörper

Target: Apelin (APLN)

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Apelin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Anti-Apelin antibody is directed against human Apelin protein.  The product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on 100% homology for the immunogen sequence.  Cross reactivity with Apelin from other sources has not been determined.

Immunogen:

Immunogen: Apelin affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human Apelin.

Immunogen Type: Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-Apelin is useful for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~8.6 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution Volume: 100 μL

Reconstitution Buffer: Restore with deionized water (or equivalent)

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

0.05 mg Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu Apelin

Target: Apelin (APLN)

Andere Bezeichnung: Apelin (APLN Produkte)

Synonyme: APLN antikoerper, Xapelin antikoerper, xnpep2 antikoerper, preproapelin antikoerper, 6030430G11Rik antikoerper, Apel antikoerper, APEL antikoerper, XNPEP2 antikoerper, apelin antikoerper, apelin S homeolog antikoerper, apln antikoerper, APLN antikoerper, apln.S antikoerper, Apln antikoerper

Hintergrund:

Synonyms: APJ endogenous ligand,

Background: Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The apelin gene to Xq25-q26.3 based on sequence similarity between the apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. This antibody is suitable for researchers interested in neuroscience research.

Gene Name: APLN

Gen-ID: 8862

NCBI Accession: NP_059109

UniProt: Q9ULZ1

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour