MUC5B Antikörper

Produktnummer ABIN6657491

Hersteller Produkt- Nr.: 200-301-p41

Dieses Anti-MUC5B-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MUC5B in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für MUC5B Antikörper (ABIN6657491)

Target: MUC5B (Mucin 5 Subtype B (MUC5B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MUC5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 45M1

Produktdetails anti-MUC5B Antikörper

Hersteller Produkt- Nr.: 200-301-p41

Hersteller: Rockland

Verwendungszweck: Mucin Gastric Antibody

Kreuzreaktivität (Details): This product reacts with human, mouse, rat, and rabbit.

Aufreinigung: Anti-Mucin Gastric antibody was purified from mouse ascites by protein A chromatography.

Immunogen: Mucin Gastric antibody was produced in mice by repeated immunizations with mucin from human ovarian cyst fluid.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:20,000

Immunohistochemistry_Dilution: 2-4 μg/mL

Western_Blot_Dilution: 1-2 μg/mL

Other: ICC: 1 μg/mL

Kommentare:

Anti-Mucin Gastric is tested for Immunocytochemistry, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~596 kDa corresponding to the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Neutral PBS

Reconstitution_Volume: 1.0 mL

Buffer:

Buffer: 1.2 % sodium acetate

Stabilizer: 2 mg BSA

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu MUC5B

Target: MUC5B (Mucin 5 Subtype B (MUC5B))

Andere Bezeichnung: MUC5B

Hintergrund:

Synonyms: MG1, MUC5, MUC9, MUC-5B, Cervical mucin, High molecular weight salivary mucin MG1, Mucin-5 subtype B, tracheobronchial, Sublingual gland mucin

Background: MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90 % breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. This antibody is suitable for researchers interested in neuroscience research, developmental signaling, and cell adheshion.

Gene Name: MUC5B

Gen-ID: 727897

NCBI Accession: NP_002449

UniProt: Q9HC84