Desmin Antikörper

Produktnummer ABIN6657489

Hersteller Produkt- Nr.: 200-301-p35

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Desmin in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Schwein.

Kurzübersicht für Desmin Antikörper (ABIN6657489)

Target: Desmin (DES)

Reaktivität: Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Desmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: DE-U-10

Produktdetails anti-Desmin Antikörper

Hersteller Produkt- Nr.: 200-301-p35

Hersteller: Rockland

Verwendungszweck: Desmin Antibody

Kreuzreaktivität (Details): This product reacts with human, mouse, rat, and rabbit.

Aufreinigung: Anti-Desmin antibody was purified from mouse ascites by protein A chromatography.

Immunogen: Desmin antibody was produced in mice by repeated immunizations with desmin from pig stomach.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:20,000

Immunohistochemistry_Dilution: 1:100-1:500

Western_Blot_Dilution: 2 μg/mL

Kommentare:

Anti-Desmin is tested for Immunohistochemistry -P and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~53.5 kDa corresponding to the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Neutral PBS

Reconstitution_Volume: 1.0 mL

Buffer:

Buffer: 1.2 % sodium acetate

Stabilizer: 2 mg BSA

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Desmin

Target: Desmin (DES)

Andere Bezeichnung: Desmin

Hintergrund:

Synonyms: CMD1I, CSM1, CSM2, intermediate filament protein

Background: Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. DES gene encodes desmin, a muscle-specific cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball (1992) found that desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al. (1989) localized the gene to 2q35. Desmin mutation responsible for idiopathic dilated cardiomyopathy. This antibody is suitable for researchers interested in cancer research, cardiovascular diseases, neurodegenerative diseases, cell adhesion research, and cytoskeletal signaling research.

Gene Name: DES

Gen-ID: 396725

NCBI Accession: NP_001001535

UniProt: P02540