Retinoic Acid Receptor beta Antikörper (N-Term)

Produktnummer ABIN6657358

Hersteller Produkt- Nr.: 209-301-e26

Der Maus Monoklonal Anti-Retinoic Acid Receptor beta-Antikörper wurde für WB validiert. Er ist geeignet, Retinoic Acid Receptor beta in Proben von Human zu detektieren.

Kurzübersicht für Retinoic Acid Receptor beta Antikörper (N-Term) (ABIN6657358)

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoic Acid Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 336

Produktdetails anti-Retinoic Acid Receptor beta Antikörper

Bindungsspezifität: N-Term

Hersteller Produkt- Nr.: 209-301-e26

Hersteller: Rockland

Verwendungszweck: Retinoic Acid Receptor beta Antibody

Kreuzreaktivität (Details): Retinoic Acid Receptor beta antibodies was Protein G purified from cell culture supernatant.

Aufreinigung: Anti-Retinoic Acid Receptor beta antibody detects Retinoic Acid Receptor beta.

Immunogen: Anti-Retinoic Acid Receptor beta was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the N-terminal region of RAR beta.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1:1000

Kommentare:

Anti-Retinoic Acid Receptor beta antibody is tested for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to expected molecular weight for RAR-β proteins in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Retinoic Acid Receptor beta

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Andere Bezeichnung: Retinoic Acid Receptor beta

Hintergrund:

Synonyms: mouse anti-Retinoic Acid Receptor beta Antibody, mouse anti-RAR-beta antibody, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon

Background: Retinoic Acid Receptor beta antibody detects RAR beta. Retinoic Acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Gene Name: RARB

Gen-ID: 5915

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway