Retinoic Acid Receptor alpha Antikörper (N-Term)

Produktnummer ABIN6657357

Hersteller Produkt- Nr.: 209-301-e25

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Retinoic Acid Receptor alpha in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Retinoic Acid Receptor alpha Antikörper (N-Term) (ABIN6657357)

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoic Acid Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 763

Produktdetails anti-Retinoic Acid Receptor alpha Antikörper

Bindungsspezifität: N-Term

Hersteller Produkt- Nr.: 209-301-e25

Hersteller: Rockland

Verwendungszweck: Retinoic Acid Receptor alpha Antibody

Kreuzreaktivität (Details): Retinoic Acid Receptor alpha antibody was Protein G purified from cell culture supernatant.

Aufreinigung: Anti-Retinoic Acid Receptor alpha antibody detects Retinoic Acid Receptor alpha.

Immunogen: Anti-Retinoic Acid Receptor alpha was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the N-terminal region of RAR-alpha.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1:1000

Kommentare:

Anti-Retinoic Acid Receptor alpha antibody is tested for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to expected molecular weight for RAR-α proteins in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Retinoic Acid Receptor alpha

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Andere Bezeichnung: Retinoic Acid Receptor alpha

Hintergrund:

Synonyms: mouse anti-Retinoic Acid Receptor alpha Antibody, mouse anti-RAR-alpha antibody, RAR-alpha, Nuclear receptor subfamily 1 group B member 1, NR1B1, Retinoic Acid Receptor, α-Isotype

Background: Retinoic Acid Receptor alpha antibody detects RAR alpha. Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Gene Name: RARA

Gen-ID: 5914

UniProt: P10276

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteine