COBRA1 Antikörper

Produktnummer ABIN6657338

Hersteller Produkt- Nr.: 200-301-d18

Dieses Anti-COBRA1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von COBRA1 in WB und ELISA. Geeignet für Human.

Kurzübersicht für COBRA1 Antikörper (ABIN6657338)

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser COBRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: F7E4

Produktdetails anti-COBRA1 Antikörper

Hersteller Produkt- Nr.: 200-301-d18

Hersteller: Rockland

Verwendungszweck: COBRA 1 Antibody

Kreuzreaktivität (Details): This antibody is directed against human COBRA 1.

Aufreinigung: Anti-COBRA 1 antibody was Protein G purified from culture supernatant.

Immunogen: Anti-COBRA1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant full length human COBRA1 purified from E.coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-COBRA 1 antibody has been tested by ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 62 kDa in size corresponding to COBRA1 proteins in neonatal rat brain lysate or other appropriate lysates.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu COBRA1

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Andere Bezeichnung: COBRA 1

Hintergrund:

Synonyms: COBRA1, Negative elongation factor B, NELF-B, Cofactor of BRCA1

Background: COBRA 1 antibody reacts with COBRA1 (cofactor of BRCA1) also known as NELF-B, which is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription. COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis. Anti-COBRA 1 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: COBRA1

Gen-ID: 25920

UniProt: Q8WX92