FTO Antikörper (N-Term)

Produktnummer ABIN6657007

Hersteller Produkt- Nr.: 200-301-d41

Der Maus Monoklonal Anti-FTO-Antikörper wurde für WB und FM validiert. Er ist geeignet, FTO in Proben von Human zu detektieren.

Kurzübersicht für FTO Antikörper (N-Term) (ABIN6657007)

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FTO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Fluorescence Microscopy (FM)

Klon: 5-2H10

Produktdetails anti-FTO Antikörper

Bindungsspezifität: N-Term

Hersteller Produkt- Nr.: 200-301-d41

Hersteller: Rockland

Verwendungszweck: FTO Antibody

Kreuzreaktivität (Details): Anti-FTO antibody is directed against human Fat mass and Obesity Related Protein.

Aufreinigung: Anti-FTO is a Protein G purified antibody from cell culture supernatant.

Immunogen: Anti-FTO Monoclonal Antibody was produced in mouse by repeated immunizations with FTO- Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IF_Microscopy_Dilution: 1:100

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-FTO (Mouse) Antibody has been tested in Western Blotting and ICC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 58 kDa in size corresponding to FTO proteins in Western blots of rat testes lysate. This antibody has also been used for immunocytochemistry with neuronal progenitor cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu FTO

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Andere Bezeichnung: FTO

Hintergrund:

Synonyms: Alpha-ketoglutarate-dependent dioxygenase FTO, KIAA1752

Background: FTO Antibody detects human FTO which is the protein encoded by FTO gene that is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake. Deletion analysis of FTO gene in mice showed that FTO is functionally involved in the control of both energy intake and energy expenditure. Anti-FTO Antibody is ideal for investigators involved in Neuroscience and Cell Metabolism.

Gene Name: FTO

Gen-ID: 79068

UniProt: Q9C0B1