CNTNAP2 Antikörper (Extracellular Domain)

Produktnummer ABIN6656679

Hersteller Produkt- Nr.: 200-301-f04

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CNTNAP2 in WB, IHC, IP und FM. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CNTNAP2 Antikörper (Extracellular Domain) (ABIN6656679)

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CNTNAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Klon: S67-25

Produktdetails anti-CNTNAP2 Antikörper

Bindungsspezifität: Extracellular Domain

Hersteller Produkt- Nr.: 200-301-f04

Hersteller: Rockland

Verwendungszweck: CASPR2 Antibody

Kreuzreaktivität (Details): A BLAST analysis was used to suggest cross-reactivity with CASPR2 from Mouse, Human, and Rat based on 100 % homology with the immunizing sequence.

Aufreinigung: Anti-CASPR2 Antibody was purified by Protein G chromatography.

Sterilität: Sterile filtered

Immunogen: CASPR2 Antibody was produced in mice by repeated immunizations with a fusion protein (extracellular domain) of human CASPR2.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

IF_Microscopy_Dilution: 1.0-10 μg/mL

Western_Blot_Dilution: 1 μg/mL

Kommentare:

Anti-CASPR2 Antibody is tested in WB, IP, and IHC. Expect a band approximately ~180kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 1X PBS, pH 7.4

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu CNTNAP2

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Andere Bezeichnung: CASPR2

Hintergrund:

Synonyms: Cntnap2, CNTP2, Contactin associated protein like 2, Cell recognition molecule Caspr2, CASPR2, KIAA0868

Background: Caspr (contactin-associated protein) is a part of the neurexin family. It lies in the paranodal section of the myelin sheath. It's role is for myelin sheath attachment along with contactin in a cis-complex (3). Caspr and Caspr2 regulate the formation of distinct axonal domains around the nodes of Ranvier. Caspr is required for the generation of a membrane barrier at the paranodal junction, whereas Caspr serves as a membrane scaffold that clusters Kv1 channels at the juxtaparanodal region. Both interact with protein 4.1B.

Gene Name: CNTNAP2

Gen-ID: 26047

NCBI Accession: NP_054860

UniProt: Q9UHC6