SIRT5 Antikörper

Produktnummer ABIN6656505

Hersteller Produkt- Nr.: 200-401-i14

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SIRT5 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SIRT5 Antikörper (ABIN6656505)

Target: SIRT5 (Sirtuin 5 (SIRT5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SIRT5 Antikörper

Hersteller Produkt- Nr.: 200-401-i14

Hersteller: Rockland

Verwendungszweck: SIRT5 Antibody

Kreuzreaktivität (Details): A BLAST analysis was used to suggest cross-reactivity with Anti-SIRT5 from human, mouse and rat based on 100 % homology with the immunizing sequence.

Aufreinigung: Anti-SIRT5 Antibody was purified by Protein G chromatography.

Immunogen: SIRT5 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to internal amino acids of human SIRT5 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1-3 μg/mL

Kommentare:

Anti-SIRT5 Antibody is tested for use in WB. Expect a band approximately 37kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.05 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Andere Bezeichnung: SIRT5

Hintergrund:

Synonyms: SIR2L5

Background: Anti-SIRT5 Antibody detects human SIRT5. SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones. Anti-SIRT5 Antibody is ideal for investigators involved in Epigenetic , chromatin, or enzyme research.

Gene Name: SIRT5

Gen-ID: 23408

NCBI Accession: NP_001180196

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interaktom