SNCA Antikörper

Produktnummer ABIN6656439

Hersteller Produkt- Nr.: 500-301-e56

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SNCA in WB, ELISA, IF, FM und MA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SNCA Antikörper (ABIN6656439)

Target: SNCA (Synuclein, alpha (SNCA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SNCA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM), Multiplex Assay (MA)

Klon: 2A7

Produktdetails anti-SNCA Antikörper

Hersteller Produkt- Nr.: 500-301-e56

Hersteller: Rockland

Verwendungszweck: Alpha Synuclein Antibody

Kreuzreaktivität (Details): Anti-Alpha Synuclein Antibody is directed against human Alpha Synuclein protein.

Aufreinigung: The antibody was purified by protein G purification from tissue culture supernatant.

Immunogen: Anti-Alpha Synuclein Antibody was produced by repeated immunizations with full length human alpha synuclein expressed in E. coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000

IF_Microscopy_Dilution: 1:500

Western_Blot_Dilution: 1:1000

Kommentare:

Alpha Synuclein antibody is tested for use in Western Blotting and IF. Specific conditions should be optimized by the end user. Expect a band of approximately 15 kDa in size corresponding to the alpha synuclein proteins in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Andere Bezeichnung: Alpha Synuclein

Hintergrund:

Synonyms: mouse anti-Alpha Synuclein Antibody, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP

Background: Alpha Synuclein Antibody detects Alpha Synuclein protein. Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson's disease (PD) and other neurodegenerative disorders. Early onset Parkinson's disease may be caused by a duplication or triplication of one of the alpha synuclein genes. Alpha-synuclein is also found in the Lewy bodies of patients with diffuse Lewy body disease and inclusions in glial cells in the brains of patients with multiple system atrophy (MSA) and amyotrophic lateral sclerosis (ALS). Anti-Alpha-synuclein antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: SNCA

Gen-ID: 6622

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity