SMAD7 Antikörper

Produktnummer ABIN6656373

Hersteller Produkt- Nr.: 200-401-i16

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMAD7 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SMAD7 Antikörper (ABIN6656373)

Target: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMAD7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SMAD7 Antikörper

Hersteller Produkt- Nr.: 200-401-i16

Hersteller: Rockland

Verwendungszweck: SMAD7 Antibody

Kreuzreaktivität (Details): A BLAST analysis was used to suggest cross-reactivity with Anti-SMAD7 from human, rat, sheep and mouse based on 100 % homology with the immunizing sequence.

Aufreinigung: Anti-SMAD7 Antibody was purified by Protein G chromatography.

Immunogen: SMAD7 Antibody was produced from whole rabbit serum prepared by repeated immunizations with SMAD7 peptide.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 2-5 μg/mL

Kommentare:

Anti-SMAD7 antibody is tested for use in WB, ELISA, and IHC. Expect a band approximately 46kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

Preservative: 0.05 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu SMAD7

Target: SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))

Andere Bezeichnung: SMAD7

Hintergrund:

Synonyms: MADH7, MADH8

Background: Anti-SMAD7 MADH7 antibody detects human SMAD7 MADH7. SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, 2, 5, 8 and 9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8 and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature. Anti-SMAD7 MADH7 antibody is ideal for investigators involved kinase and phosphatase research.

Gene Name: SMAD7

Gen-ID: 4092

NCBI Accession: NP_001177750

UniProt: O15105

Pathways: Interferon-gamma Pathway, Cell-Cell Junction Organization