KDELR1 Antikörper

Produktnummer ABIN6656145

Hersteller Produkt- Nr.: 600-401-f85

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KDELR1 in WB, IF und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KDELR1 Antikörper (ABIN6656145)

Target: KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDELR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-KDELR1 Antikörper

Hersteller Produkt- Nr.: 600-401-f85

Hersteller: Rockland

Verwendungszweck: KDEL Antibody

Kreuzreaktivität (Details): A BLAST analysis was used to suggest cross-reactivity with KDEL from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

Aufreinigung: Anti-KDEL Antibody was purified by affinity chromatography.

Sterilität: Sterile filtered

Immunogen: KDEL Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against KDEL containing synthetic peptide immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1:1000

Kommentare:

Anti-KDEL Antibody is tested for use in WB, IF, and IHC. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu KDELR1

Target: KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))

Andere Bezeichnung: KDELR1

Hintergrund:

Synonyms: Lys Asp Glu Leu, K-D-E-L, ER lumen protein retaining receptor 1, KDEL endoplasmic reticulum protein retention, Kdelr1

Background: The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER.

Gene Name: Kdelr1

Gen-ID: 10945

NCBI Accession: NP_006792

UniProt: P24390

Pathways: Maintenance of Protein Location