SETD8 Antikörper
Kurzübersicht für SETD8 Antikörper (ABIN6655982)
Target
Alle SETD8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Hersteller Produkt- Nr.
- 100-401-v82
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Hersteller
- Rockland
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Verwendungszweck
- SETD8 Antibody
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Kreuzreaktivität (Details)
- Cross reactivity with SETD8 from species other than human and mouse not tested.
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Aufreinigung
- Anti-SETD8 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
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Sterilität
- Sterile filtered
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Immunogen
- Anti-SETD8 Antibody was produced in rabbits by repeated immunizations of the full length human SETD8 protein containing a Flag-tagged N-terminus and a His-tagged C terminus.
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Isotyp
- IgG
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Applikationshinweise
- Optional[Neutralization_Dilution]: 1:1,000
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Kommentare
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Anti-SETD8 Antibody has been tested by western blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 40 kDa in the appropriate cell lysate or extract.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide -
Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Haltbarkeit
- 12 months
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- SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
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Andere Bezeichnung
- SETD8
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Hintergrund
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Synonyms: N-lysine methyltransferase SETD8, H4-K20-HMTase SETD8, Histone-lysine N-methyltransferse SETD8, Lysine N-methyltransferase 5A, PR/SET domain-containing protein 07, SET domain-containing protein 8, PR-Set7, PR/SET07
Background: SETD8 is a histone methyl transferase that specifically monomethylates 'Lys-20' of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression and is enriched during mitosis. SETD8 may also play a role in maintaining silet chromatin by preventing the acetylation of the H4 tail. Anti-SETD8 Antibody is ideal for research in Gene Expression, Epigenetics and Chromatin Remodeling.
Gene Name: SETD8
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Gen-ID
- 387893
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NCBI Accession
- NP_065115
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UniProt
- Q9NQR1
Target
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