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THRB Antikörper (N-Term)

THRB Reaktivität: Human WB Wirt: Maus Monoclonal 2386 unconjugated
Rockland
Produktnummer ABIN6655581
Hersteller Produkt- Nr.: 209-301-a96
  • Target Alle THRB Antikörper anzeigen
    THRB (Thyroid Hormone Receptor, beta (THRB))
    Bindungsspezifität
    • 16
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 59
    • 32
    • 32
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Human
    Wirt
    • 58
    • 6
    • 1
    Maus
    Klonalität
    • 59
    • 6
    Monoklonal
    Konjugat
    • 40
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser THRB Antikörper ist unkonjugiert
    Applikation
    • 55
    • 23
    • 19
    • 15
    • 13
    • 13
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Hersteller Produkt- Nr.
    209-301-a96
    Hersteller
    Rockland
    Verwendungszweck
    Thyroid Hormone Receptor beta Antibody
    Kreuzreaktivität (Details)
    Thyroid Hormone Receptor beta antibody is purified by Protein G chromatography from cell culture supernatant.
    Aufreinigung
    Anti-Thyroid Hormone Receptor beta antibody is directed against human TRβ.
    Immunogen
    Anti-Thyroid Hormone Receptor beta monoclonal antibody was produced in mouse by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region of Thyroid Hormone Receptor beta.
    Klon
    2386
    Isotyp
    IgG1
    Top Product
    Discover our top product THRB Primärantikörper
  • Applikationshinweise
    Optional[Neutralization_Dilution]: 1:1000
    Kommentare

    Suggested Applications: IHC
    Anti-Thyroid Hormone Receptor beta (Mouse) antibody is tested for use in Western Blotting. Expect a band of approximately 55 kDa corresponding to TR-β proteins in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Aksoy, Pencik, Hartenbach, Moazzami, Schlederer, Balber, Varady, Philippe, Baltzer, Mazumder, Whitchurch, Roberts, Haitel, Herac, Susani, Mitterhauser, Marculescu, Stangl-Kremser, Hassler, Kramer, Shariat, Turner, Tichy, Oppelt, Pospisilova, Hartenbach, T: "Thyroid and androgen receptor signaling are antagonized by μ-Crystallin in prostate cancer." in: International journal of cancer, Vol. 148, Issue 3, pp. 731-747, (2021) (PubMed).

    Schnoell, Kotowski, Jank, Stoiber, Gurnhofer, Schlederer, Heiduschka, Kenner, Kadletz-Wanke: "Prognostic Relevance of Thyroid-Hormone-Associated Proteins in Adenoid Cystic Carcinoma of the Head and Neck." in: Journal of personalized medicine, Vol. 11, Issue 12, (2021) (PubMed).

  • Target
    THRB (Thyroid Hormone Receptor, beta (THRB))
    Andere Bezeichnung
    Thyroid Hormone Receptor beta (THRB Produkte)
    Hintergrund

    Synonyms: mouse anti-Thyroid Hormone Receptor beta Antibody, mouse anti-Thrb antibody, Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta

    Background: Thyroid Hormone Receptor beta antibody detects Thyroid Hormone Receptor beta. Thyroid hormones are essential for development of the central nervous system and deficits in these hormones during development affects such cognitive functions as learning and memory. Thyroid hormones exert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRα1, TRα2, TRβ1 and TRβ2. TRα1, TRβ1 and TRβ2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain. Thyroid Hormone Receptor beta antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

    Gene Name: THRB

    Gen-ID
    7068
    NCBI Accession
    NP_000452
    UniProt
    P10828
    Pathways
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound
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