CD19 Antikörper (FITC)

Produktnummer ABIN6655429

Hersteller Produkt- Nr.: 200-302-n24

Der Maus Monoklonal Anti-CD19-Antikörper wurde für FACS validiert. Er ist geeignet, CD19 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für CD19 Antikörper (FITC) (ABIN6655429)

Target: CD19 (CD19 Molecule (CD19))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD19 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: HIB19

Produktdetails anti-CD19 Antikörper (FITC)

Hersteller Produkt- Nr.: 200-302-n24

Hersteller: Rockland

Verwendungszweck: CD19 Fluorescein Antibody

Kreuzreaktivität (Details): Reactivity is observed against human CD19 and chimpanzee.

Aufreinigung: Fluorescein conjugated CD19 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD19.

Sterilität: Sterile filtered

Immunogen: Anti-CD19 Antibody (Monoclonal) was produced by repeated immunizations with CD19 antigen.

Isotyp: IgG1 kappa

Labeling Ratio: 4-6

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 5 µL/1x10e6 cells or 100μL of whole blood

Kommentare:

Anti-CD19 is tested for Flow Cytometry. Researchers should determine optimal titers for applications that are not stated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.2 % BSA (w/v)

Preservative: 0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

Haltbarkeit: 6 months

Referenzen für anti-CD19 Antikörper (FITC) (ABIN6655429)

Bradbury, Goldmacher, Tedder: "The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 6, pp. 2915-27, (1993) (PubMed).

Details zu CD19

Target: CD19 (CD19 Molecule (CD19))

Andere Bezeichnung: CD19

Hintergrund:

Synonyms: B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19

Background: CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.

Gene Name: CD19

Gen-ID: 930

NCBI Accession: NP_001171569

UniProt: P15391

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung