L-Selectin Antikörper (PE)

Produktnummer ABIN6655168

Hersteller Produkt- Nr.: 200-308-n72

Der Maus Monoklonal Anti-L-Selectin-Antikörper wurde für FACS und WB validiert. Er ist geeignet, L-Selectin in Proben von Human zu detektieren.

Kurzübersicht für L-Selectin Antikörper (PE) (ABIN6655168)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser L-Selectin Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Western Blotting (WB)

Klon: DREG-56

Produktdetails anti-L-Selectin Antikörper (PE)

Hersteller Produkt- Nr.: 200-308-n72

Hersteller: Rockland

Verwendungszweck: CD62L Phycoerythrin Antibody

Kreuzreaktivität (Details): Reactivity is observed against human CD62L.

Aufreinigung: Phycoerythrin conjugated CD62L Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD62L.

Sterilität: Sterile filtered

Immunogen: Anti-CD62L Antibody (Monoclonal) was produced by repeated immunizations with CD62L antigen.

Isotyp: IgG1 kappa

Labeling Ratio: 1-2

Anwendungsinformationen

Applikationshinweise:

Flow_Cytometry_Dilution: 5 uL/test/1x10e5 to 1x10e8 cells

Western_Blot_Dilution: User Optimized

Kommentare:

Anti-CD62L is tested for Flow Cytometry and useful in Western Blot. Researchers should determine optimal titers for applications that are not stated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.2 % BSA (w/v)

Preservative: 0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Haltbarkeit: 6 months

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: CD62L

Hintergrund:

Synonyms: L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, TQ1, gp90-MEL, CD62L , SELL , LNHR, LYAM1

Background: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

Gene Name: SELL

Gen-ID: 6402

NCBI Accession: NP_000646

UniProt: P14151