Calretinin Antikörper

Produktnummer ABIN6655054

Produktdetails anti-Calretinin Antikörper

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Reaktivität: Meerschweinchen

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser Calretinin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Fluorescence Microscopy (FM)

Kreuzreaktivität: Meerschweinchen, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reactivity with Calretinin from other species has not been determined

Aufreinigung: Anti-Calretinin Antibody is directed against guinea pig Calretinin protein. The antibody was purified from monospecific antiserum by Protein A chromatography. Anti-Calretinin antibody reacts with Calretinin from rat and guinea pig sources. . However, reactivity is also expected from the following species based on 100% sequence homology: human, mouse, non-human primates.

Immunogen:

Immunogen: Anti-Calretinin Antibody was produced by repeated immunizations with native guinea pig calretinin.

Immunogen Type: Native Protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 1:500

Application Note: Anti-Calretinin antibody is suitable for use in ELISA, Western Blotting, IHC and IF. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 29 kDa in size corresponding to the calretinin protein in Western blots using rat brain lysate. Use this calretinin antibody for Immunohistochemistry on formalin or paraformaldehyde perfused rat brain tissue sections.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

IF Microscopy Dilution: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M Tris Cl, 0.15 M Sodium Chloride, 0.001 M EDTA, pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Referenzen für anti-Calretinin Antikörper (ABIN6655054)

Molgaard, Ulrichsen, Boggild, Holm, Vaegter, Nyengaard, Glerup: "Immunofluorescent visualization of mouse interneuron subtypes." in: F1000Research, Vol. 3, pp. 242, (2014) (PubMed).

Details zu Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Andere Bezeichnung: Calretinin (CALB2 Produkte)

Synonyme: CAB29 antikoerper, CAL2 antikoerper, CR antikoerper, calb2l antikoerper, wu:fq18e08 antikoerper, zgc:73115 antikoerper, calb2 antikoerper, wu:fq17g09 antikoerper, zgc:73099 antikoerper, calbindin 2 antikoerper, calbindin 2a antikoerper, calbindin 2b antikoerper, CALB2 antikoerper, Calb2 antikoerper, calb2a antikoerper, calb2b antikoerper

Hintergrund:

Synonyms: CR, Calb2, CAB29

Background: Calretinin antibody reacts with calretinin which is a calcium-binding protein involved in calcium signaling. Calretinin is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium. Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas. Anti-Calretinin antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: CALB2

Gen-ID: 117059

NCBI Accession: NP_446440

UniProt: P47728